Inventory organization should make decisions faster. The best system is one where useful consumables and active equipment are easy to find during play.
Keep combat consumables visible
Potions, scrolls and situational items are more valuable when they can be found quickly.
Separate active gear from experiments
Move unused alternatives out of the main decision space until you are ready to compare them.
Remove obvious clutter regularly
Selling or moving low-value items prevents the inventory from becoming a search problem.
Distribute items by character role
Put useful items on the characters most likely to use them so access is faster during combat.